All | Archetype [runtimeNameConstraintForConceptName=null, archetypeConceptBinding=null, archetypeConceptDescription=The Liver Imaging Reporting and Data System (LI-RADS®) is a comprehensive system for standardizing the terminology, technique, interpretation, reporting, and data collection of liver observations in individuals at high risk for hepatocellular carcinoma (HCC)., archetypeConceptComment=null, otherContributors=, originalLanguage=en, translators=German: Samer Alkarkoukly, Uniklinik Köln, mabbouda@uni-koeln.de , subjectOfData=unconstrained, archetypeTranslationTree=null, topLevelToAshis={provider=[], target=[], capabilities=[], other_participations=[], content=[], identities=[], details=[], credentials=[], ism_transition=[], relationships=[], data=[], context=[], state=[], description=[], events=[], protocol=[], contacts=[], source=[], items=[ResourceSimplifiedHierarchyItem [path=/items[at0003], code=at0003, itemType=ELEMENT, level=1, text=LI-RADS algorithm, description=The algorithm used to assess and diagnose liver lesions in a patient at risk of HCC., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=- at0004::Ultrasound LI-RADS [For monitoring. Using conventional sonography. In patients with liver cirrhosis and other high-risk patients.]
- at0005::CEUS LI-RADS [For HCC diagnostics. Using contrast-enhanced ultrasound (KMUS, contrast-enhanced.]
- at0006::CT/MRI Diagnostic LI-RADS [For HCC diagnosis and staging. In patients with liver cirrhosis and other high-risk patients including transplant candidates with HCC.]
- at0007::CT/MRI therapy response LI-RADS [To assess HCC therapy response to locoregional therapy. In patients with liver cirrhosis and other high-risk patients including transplant candidates with HCC. Using CT, MRI with extracellular contrast agents (ECA), or MRI with hepatobiliary contrast agents (HBA).]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0008], code=at0008, itemType=ELEMENT, level=1, text=LI-RADS Version, description=The year of the LI-RADS version used to assess and diagnose the patient., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0009], code=at0009, itemType=ELEMENT, level=1, text=Diagnostic category, description=The LI-RADS category is a score assigned to a focal lesion. The categories span the spectrum of benign to malignant observations occurring in patients with chronic liver disease at risk for cirrhosis., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=- at0010::LR-NC [If assessment is not possible due to missing or poor imaging.]
- at0011::LR-TIV [If there is definitive evidence of tumor infiltration into the vein (TIV).]
- at0012::LR-1 [If definitely benign.]
- at0013::LR-2 [If probably benign.]
- at0014::LR-3 [With medium probability of malignancy.]
- at0015::LR-4 [If probably HCC.]
- at0016::LR-5 [Wenn definitiv HCC.]
- at0017::LR-M [If probably or definitely malignant but not HCC-specific (e.g. bull's-eye sign).]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0018], code=at0018, itemType=ELEMENT, level=1, text=Therapy response category, description=The categories of therapy response (TR) are used to assess the tumor's response after a locoregional therapy., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=- at0019::LR-TR Not assessable [Treated, response not assessable (due to lack of imaging or poor quality).]
- at0020::LR-TR nonviable [Treated, probably or definitely nonviable.]
- at0021::LR-TR not clear [Treated, not clearly vital.]
- at0022::LR-TR vital [Treated, probably or definitely vital.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0023], code=at0023, itemType=ELEMENT, level=1, text=Arterial hypervascularization (APHE), description=The enhancement in the arterial phase, which is clearly higher than that of the liver., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=- at0025::No APHE [No contrast enhancement in the arterial phase.]
- at0026::APHE (no rim character) [Contrast enhancement in the arterial phase, non-marginal.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0027], code=at0027, itemType=ELEMENT, level=1, text=Size of the observation, description=The size of the observed nodule or lesion in the liver., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CHOICE, bindings=null, values=Choice of:
Quantity Property: Length Units: mm Text
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0028], code=at0028, itemType=ELEMENT, level=1, text=Enhancing capsule, description=Peripheral edge of a smooth hyperenhancement in the portal venous phase, transition phase or delayed phase., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=- at0029::Yes [With enhancing capsule.]
- at0030::No [Without enhancing of the capsule.]
- at0053::Unknown [Cannot be evaluated or not clear.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0031], code=at0031, itemType=ELEMENT, level=1, text=“Washout” (not peripheral), description=A visual assessment of the relative hypointensity of the lesion compared to the background liver in the portal venous and delayed phases., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=- at0032::Yes [With washout.]
- at0033::No [Without washout.]
- at0054::Unknown [Cannot be evaluated or not clear.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0034], code=at0034, itemType=ELEMENT, level=1, text=Threshold growth, description=Diameter increase ≥50% increase in ≤6 months. Other previous criteria are now considered subthreshold growth, an additional feature (if the previous examination lasts >6 months, the diameter increases ≥100%, or if a new lesion ≥10 mm arises in <24 months)., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=- at0035::Yes [With threshold growth.]
- at0036::No [Without threshold growth.]
- at0055::Unknown [Cannot be evaluated or not clear.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0037], code=at0037, itemType=ELEMENT, level=1, text=Vascular involvement, description=The presence of clear improving soft tissue in the vessel lumen., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=- at0038::Yes [With vascular involvement.]
- at0039::No [Without vascular involvement.]
- at0056::Unknown [Cannot be evaluated or not clear.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0040], code=at0040, itemType=ELEMENT, level=1, text=Comment, description=Additional information about the report that has not yet been documented elsewhere., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null]], activities=[]}, topLevelItems={items=ResourceSimplifiedHierarchyItem [path=ROOT_/, code=at0000, itemType=CLUSTER, level=0, text=null, description=null, comment=null, uncommonOntologyItems=null, occurencesFormal=1..1, occurencesText=Mandatory, cardinalityFormal=1..*, cardinalityText= (Cardinality: 1..*, unordered), subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=null, extendedValues=null]}, addHierarchyItemsTo=items, currentHierarchyItemsForAdding=[ResourceSimplifiedHierarchyItem [path=/items[at0003], code=at0003, itemType=ELEMENT, level=1, text=LI-RADS algorithm, description=The algorithm used to assess and diagnose liver lesions in a patient at risk of HCC., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=- at0004::Ultrasound LI-RADS [For monitoring. Using conventional sonography. In patients with liver cirrhosis and other high-risk patients.]
- at0005::CEUS LI-RADS [For HCC diagnostics. Using contrast-enhanced ultrasound (KMUS, contrast-enhanced.]
- at0006::CT/MRI Diagnostic LI-RADS [For HCC diagnosis and staging. In patients with liver cirrhosis and other high-risk patients including transplant candidates with HCC.]
- at0007::CT/MRI therapy response LI-RADS [To assess HCC therapy response to locoregional therapy. In patients with liver cirrhosis and other high-risk patients including transplant candidates with HCC. Using CT, MRI with extracellular contrast agents (ECA), or MRI with hepatobiliary contrast agents (HBA).]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0008], code=at0008, itemType=ELEMENT, level=1, text=LI-RADS Version, description=The year of the LI-RADS version used to assess and diagnose the patient., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0009], code=at0009, itemType=ELEMENT, level=1, text=Diagnostic category, description=The LI-RADS category is a score assigned to a focal lesion. The categories span the spectrum of benign to malignant observations occurring in patients with chronic liver disease at risk for cirrhosis., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=- at0010::LR-NC [If assessment is not possible due to missing or poor imaging.]
- at0011::LR-TIV [If there is definitive evidence of tumor infiltration into the vein (TIV).]
- at0012::LR-1 [If definitely benign.]
- at0013::LR-2 [If probably benign.]
- at0014::LR-3 [With medium probability of malignancy.]
- at0015::LR-4 [If probably HCC.]
- at0016::LR-5 [Wenn definitiv HCC.]
- at0017::LR-M [If probably or definitely malignant but not HCC-specific (e.g. bull's-eye sign).]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0018], code=at0018, itemType=ELEMENT, level=1, text=Therapy response category, description=The categories of therapy response (TR) are used to assess the tumor's response after a locoregional therapy., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=- at0019::LR-TR Not assessable [Treated, response not assessable (due to lack of imaging or poor quality).]
- at0020::LR-TR nonviable [Treated, probably or definitely nonviable.]
- at0021::LR-TR not clear [Treated, not clearly vital.]
- at0022::LR-TR vital [Treated, probably or definitely vital.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0023], code=at0023, itemType=ELEMENT, level=1, text=Arterial hypervascularization (APHE), description=The enhancement in the arterial phase, which is clearly higher than that of the liver., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=- at0025::No APHE [No contrast enhancement in the arterial phase.]
- at0026::APHE (no rim character) [Contrast enhancement in the arterial phase, non-marginal.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0027], code=at0027, itemType=ELEMENT, level=1, text=Size of the observation, description=The size of the observed nodule or lesion in the liver., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CHOICE, bindings=null, values=Choice of:
Quantity Property: Length Units: mm Text
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0028], code=at0028, itemType=ELEMENT, level=1, text=Enhancing capsule, description=Peripheral edge of a smooth hyperenhancement in the portal venous phase, transition phase or delayed phase., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=- at0029::Yes [With enhancing capsule.]
- at0030::No [Without enhancing of the capsule.]
- at0053::Unknown [Cannot be evaluated or not clear.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0031], code=at0031, itemType=ELEMENT, level=1, text=“Washout” (not peripheral), description=A visual assessment of the relative hypointensity of the lesion compared to the background liver in the portal venous and delayed phases., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=- at0032::Yes [With washout.]
- at0033::No [Without washout.]
- at0054::Unknown [Cannot be evaluated or not clear.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0034], code=at0034, itemType=ELEMENT, level=1, text=Threshold growth, description=Diameter increase ≥50% increase in ≤6 months. Other previous criteria are now considered subthreshold growth, an additional feature (if the previous examination lasts >6 months, the diameter increases ≥100%, or if a new lesion ≥10 mm arises in <24 months)., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=- at0035::Yes [With threshold growth.]
- at0036::No [Without threshold growth.]
- at0055::Unknown [Cannot be evaluated or not clear.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0037], code=at0037, itemType=ELEMENT, level=1, text=Vascular involvement, description=The presence of clear improving soft tissue in the vessel lumen., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=- at0038::Yes [With vascular involvement.]
- at0039::No [Without vascular involvement.]
- at0056::Unknown [Cannot be evaluated or not clear.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0040], code=at0040, itemType=ELEMENT, level=1, text=Comment, description=Additional information about the report that has not yet been documented elsewhere., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null]], minIndents={}, termBindingRetrievalErrorMessage=null] |