ARCHETYPE Examination of a blastocyst (openEHR-EHR-CLUSTER.exam_blastocyst.v1)

ARCHETYPE IDopenEHR-EHR-CLUSTER.exam_blastocyst.v1
ConceptExamination of a blastocyst
DescriptionMorphological findings obtained by microscopy of a human blastocyst.
UseUse to record morphological observations about a human blastocyst, usually as part of assisted reproduction treatment. This archetype has been specifically designed to be used in the 'Observations detail' SLOT within the 'OBSERVATION.embryo_assessment' or 'ACTION.procedure' archetype, but can also be used within other ENTRY or CLUSTER archetypes, where clinically appropriate.
MisuseNot to be used for recording observations on oocytes, zygotes and cleavage stage embryos - use specific CLUSTER archetypes for this purpose.
PurposeTo record structured observations about a human blastocyst.
ReferencesAlpha Scientists in Reproductive, M. and E.S.I.G.o. Embryology, The Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting. Human Reproduction, 2011. 26(6): p. 1270-1283.

Hardarson, T., L. Van Landuyt, and G. Jones, The blastocyst. Human Reproduction, 2012. 27(suppl_1): p. i72-i91.
Copyright© openEHR Foundation
AuthorsAuthor name: Peter Fedorcsak
Organisation: Oslo University Hospital
Email: peter.fedorcsak@medisin.uio.no
Date originally authored: 2021-10-26
Other Details LanguageAuthor name: Peter Fedorcsak
Organisation: Oslo University Hospital
Email: peter.fedorcsak@medisin.uio.no
Date originally authored: 2021-10-26
Other Details (Language Independent)
  • Licence: This work is licensed under the Creative Commons Attribution-ShareAlike 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-sa/4.0/.
  • Custodian Organisation: openEHR Foundation
  • References: Alpha Scientists in Reproductive, M. and E.S.I.G.o. Embryology, The Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting. Human Reproduction, 2011. 26(6): p. 1270-1283. Hardarson, T., L. Van Landuyt, and G. Jones, The blastocyst. Human Reproduction, 2012. 27(suppl_1): p. i72-i91.
  • Original Namespace: org.openehr
  • Original Publisher: openEHR Foundation
  • Custodian Namespace: org.openehr
  • MD5-CAM-1.0.1: 25DE1CB79E30B209FCE47B998AFF3008
  • Build Uid: 80f141a3-30aa-4a8d-a8b5-921a03bac275
  • Revision: 1.0.1
Keywordsin vitro, fertilization, IVF, reproductive medicine, zygote, fertilised, fertilized, oocyte, egg, fertilisation, embryo, reproduction, ART, blastocyst
Lifecyclepublished
UID217e48d9-a3b5-48c5-bf7d-efef3c16b7b7
Language useden
Citeable Identifier1246.145.2671
Revision Number1.0.1
items
Degree of expansionDegree of expansion: Degree of expansion of the blastocyst.
Choice of:
  •  Coded Text
    • Grade 1 [The blastocoel cavity is less than the half of the embryo volume.]
    • Grade 2 [The blastocoel cavity is > 50% of the embryo volume.]
    • Grade 3 [The blastocoel cavity completely fills the embryo volume.]
    • Grade 4 [The blastocoel cavity is larger than the original volume of the embryo, thinned zona pellucida.]
    • Grade 5 [Hatching blastocyst.]
    • Grade 6 [Completely hatched blastocyst.]
  •  Text
Inner cell mass morphologyInner cell mass morphology: Morphology of the inner cell mass.
Choice of:
  •  Coded Text
    • A [The inner call mass contains many tightly packed cells.]
    • B [The inner call mass contains several loosely grouped cells.]
    • C [The inner call mass contains few loosely bound cells.]
    • Not accessible [Inner cell mass morphology is not accessible.]
  •  Text
Trophectoderm morphologyTrophectoderm morphology: Morphology of the trophectoderm of the blastocyst.
Choice of:
  •  Coded Text
    • A [Trophectoderm contains many cells that form a cohesive epithelium.]
    • B [Trophectoderm contains few cells that form a loose epithelium.]
    • C [Trophectoderm contains very few large cells that struggle to form a cohesive epithelium.]
  •  Text
Other morphological featuresOther morphological features: Additional morphological features of the blastocyst not captured by specific parameters.
For example: signs of degeneration, such as presence of necrosis and exclusion of cells; cellular bridges, vacuolation; or multiple hatching points. The occurrences for this data element is set to 0..* to allow for more than one morphological attribute to be added as a coded value.
Morphology gradeMorphology grade: Overall grading or score based on recorded morphological features of the blastocyst.
Use of an established morphology assessment classification is preferred.
Other contributorsVebjørn Arntzen, Oslo University Hospital, Norway (openEHR Editor)
SB Bhattacharyya, Bhattacharyyas Clinical Records Research & Informatics LLP, India
Peter Fedorcsak, University of Oslo, Norway (openEHR Editor)
Rosane Gotardo, Systema Ltda., Brazil
Heather Grain, Llewelyn Grain Informatics, Australia
Gareth Greggains, Oslo University Hospital
Liv Laugen, ​Oslo University Hospital, Norway, Norway (openEHR Editor)
Heather Leslie, Atomica Informatics, Australia (openEHR Editor)
Manisha Mantri, C-DAC, India
Mikael Nyström, Cambio Healthcare Systems AB, Sweden
Trine Skuland, Oslo University Hospital
Norwegian Review Summary, Nasjonal IKT HF, Norway
Julius Hreinsson, Laboratory Director at Reproductive Medicine, Sahlgrenska University Hospital, Sweden
Translators
  • Norwegian Bokmål: Peter Fedorcsak, Vebjørn Arntzen, University of Oslo, Oslo University Hospital, peterfe@uio.no, varntzen@ous-hf.no