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    <original_author id="date">2019-06-08</original_author>
    <original_author id="name">Henry Lenzi</original_author>
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    <other_details id="licence">This work is licensed under the Creative Commons Attribution-ShareAlike 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-sa/4.0/.</other_details>
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    <other_details id="references">Abernethy AP, Shelby-James T, Fazekas BS, Woods D, Currow DC. The Australia-modified Karnofsky Performance Status (AKPS) scale: a revised scale for contemporary palliative care clinical practice [ISRCTN81117481]. BMC Palliat Care. 2005 Nov 12;4:7. doi: 10.1186/1472-684X-4-7. PMID: 16283937; PMCID: PMC1308820. Available from: https://bmcpalliatcare.biomedcentral.com/articles/10.1186/1472-684X-4-7.&#xD;
&#xD;
ECOG-ACRIN Cancer Research Group [Internet]. Philadelphia: ECOG-ACRIN Cancer Research Group; 2022. ECOG Performance Status Scale; [cited 2022 Jun 03]. Available from: https://ecog-acrin.org/resources/ecog-performance-status/#.&#xD;
&#xD;
Helsedirektoratet. Nasjonalt handlingsprogram for palliasjon i kreftomsorgen. 2019. Available from: https://www.helsedirektoratet.no/retningslinjer/palliasjon-i-kreftomsorgen-handlingsprogram/.&#xD;
&#xD;
Karnofsky DA, Burchenal JH. The clinical evaluation of chemotherapeutic agents in cancer. In: MacLeod CM, ed. Evaluation of Chemotherapeutic Agents. New York, Columbia University Press, 1949.&#xD;
&#xD;
Oncoline [Online]. Integraal Kankercentrum Nederland. Appendix 1 - Karnofsky/ECOG Performance Status. [cited 2022 Jun 05]. Available from: https://www.oncoline.nl/uploaded/docs/Depressie/Bijlage%20Karnofsky.pdf.</other_details>
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Obwohl in diesem Archetyp auf die Originalarbeit von Karnofsky et al. aus dem Jahr 1949 verwiesen wird, war es nicht möglich, eine Nachbildung zu erhalten, um den ursprünglichen Inhalt sicherzustellen. Dieser Archetyp wurde jedoch so konzipiert, dass er eher die praktische Verwendung den Karnofsky-Index als ein akademisches Konstrukt widerspiegelt, und der aktuelle Wortlaut spiegelt Beschreibungen wider, die in den anderen Referenzen allgemein verwendet werden.</use>
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          <lower_unbounded>false</lower_unbounded>
          <upper_unbounded>false</upper_unbounded>
          <lower>1</lower>
          <upper>1</upper>
        </occurrences>
        <node_id>at0016</node_id>
        <attributes xsi:type="C_MULTIPLE_ATTRIBUTE">
          <rm_attribute_name>items</rm_attribute_name>
          <existence>
            <lower_included>true</lower_included>
            <upper_included>true</upper_included>
            <lower_unbounded>false</lower_unbounded>
            <upper_unbounded>false</upper_unbounded>
            <lower>0</lower>
            <upper>1</upper>
          </existence>
          <children xsi:type="ARCHETYPE_SLOT">
            <rm_type_name>CLUSTER</rm_type_name>
            <occurrences>
              <lower_included>true</lower_included>
              <lower_unbounded>false</lower_unbounded>
              <upper_unbounded>true</upper_unbounded>
              <lower>0</lower>
            </occurrences>
            <node_id>at0017</node_id>
            <includes>
              <string_expression>archetype_id/value matches {/.*/}</string_expression>
              <expression xsi:type="EXPR_BINARY_OPERATOR">
                <type>Boolean</type>
                <operator>2007</operator>
                <precedence_overridden>false</precedence_overridden>
                <left_operand xsi:type="EXPR_LEAF">
                  <type>String</type>
                  <item xsi:type="xsd:string">archetype_id/value</item>
                  <reference_type>attribute</reference_type>
                </left_operand>
                <right_operand xsi:type="EXPR_LEAF">
                  <type>C_STRING</type>
                  <item xsi:type="C_STRING">
                    <pattern>.*</pattern>
                  </item>
                  <reference_type>constraint</reference_type>
                </right_operand>
              </expression>
            </includes>
          </children>
          <cardinality>
            <is_ordered>false</is_ordered>
            <is_unique>false</is_unique>
            <interval>
              <lower_included>true</lower_included>
              <lower_unbounded>false</lower_unbounded>
              <upper_unbounded>true</upper_unbounded>
              <lower>0</lower>
            </interval>
          </cardinality>
        </attributes>
      </children>
    </attributes>
  </definition>
  <ontology>
    <term_definitions language="en">
      <items code="at0000">
        <items id="text">Karnofsky Performance Status (KPS) scale</items>
        <items id="description">An assessment scale used to quantify functional capacity in an individual.</items>
      </items>
      <items code="at0001">
        <items id="text">History</items>
        <items id="description">@ internal @</items>
      </items>
      <items code="at0002">
        <items id="text">Any point in time event</items>
        <items id="description">Default, unspecified point in time event which may be explicitly defined in a template or at run-time.</items>
      </items>
      <items code="at0003">
        <items id="text">Tree</items>
        <items id="description">@ internal @</items>
      </items>
      <items code="at0004">
        <items id="text">Karnofsky performance status</items>
        <items id="description" />
      </items>
      <items code="at0005">
        <items id="text">Dead</items>
        <items id="description" />
      </items>
      <items code="at0006">
        <items id="text">Moribund; fatal processes progressing rapidly.</items>
        <items id="description" />
      </items>
      <items code="at0007">
        <items id="text">Very sick; hospital admission necessary; active supportive treatment necessary</items>
        <items id="description" />
      </items>
      <items code="at0008">
        <items id="text">Severely disabled; hospital admission is indicated although death not imminent</items>
        <items id="description" />
      </items>
      <items code="at0009">
        <items id="text">Disabled; requires special care and assistance</items>
        <items id="description" />
      </items>
      <items code="at0010">
        <items id="text">Requires considerable assistance and frequent medical care</items>
        <items id="description" />
      </items>
      <items code="at0011">
        <items id="text">Requires occasional assistance, but is able to care for most of his personal needs</items>
        <items id="description" />
      </items>
      <items code="at0012">
        <items id="text">Cares for self; unable to carry on normal activity or to do active work</items>
        <items id="description" />
      </items>
      <items code="at0013">
        <items id="text">Normal activity with effort; some signs or symptoms of disease</items>
        <items id="description" />
      </items>
      <items code="at0014">
        <items id="text">Able to carry on normal activity; minor signs or symptoms of disease</items>
        <items id="description" />
      </items>
      <items code="at0015">
        <items id="text">Normal; no complaints; no evidence of disease</items>
        <items id="description" />
      </items>
      <items code="at0016">
        <items id="text">Item tree</items>
        <items id="description">@ internal @</items>
      </items>
      <items code="at0017">
        <items id="text">Extension</items>
        <items id="description">Additional information required to extend the model with local content or to align with other reference models or formalisms.</items>
        <items id="comment">For example: local information requirements; or additional metadata to align with FHIR.</items>
      </items>
    </term_definitions>
    <term_definitions language="pt">
      <items code="at0000">
        <items id="text">*Karnofsky Performance Status (KPS) scale (en)</items>
        <items id="description">*An assessment scale used to quantify functional capacity in an individual. (en)</items>
      </items>
      <items code="at0001">
        <items id="text">History</items>
        <items id="description">@ internal @</items>
      </items>
      <items code="at0002">
        <items id="text">Qualquer evento pontual</items>
        <items id="description">*Default, unspecified point in time event which may be explicitly defined in a template or at run-time. (en-au)</items>
      </items>
      <items code="at0003">
        <items id="text">Tree</items>
        <items id="description">@ internal @</items>
      </items>
      <items code="at0004">
        <items id="text">Status de desempenho</items>
        <items id="description">*</items>
      </items>
      <items code="at0005">
        <items id="text">Morto</items>
        <items id="description">*</items>
      </items>
      <items code="at0006">
        <items id="text">Moribundo, processo fatal progredindo rapidamente</items>
        <items id="description">*</items>
      </items>
      <items code="at0007">
        <items id="text">Incapacitado, necessita de cuidados especiais e assitência</items>
        <items id="description">*</items>
      </items>
      <items code="at0008">
        <items id="text">Gravemente incapacitado, hospitalização indicada embora morte não seja iminente</items>
        <items id="description">*</items>
      </items>
      <items code="at0009">
        <items id="text">Hospitalização necessária, muito doente, necessário tratamento ativo de suporte</items>
        <items id="description">*</items>
      </items>
      <items code="at0010">
        <items id="text">Requer assistência considerável e cuidados médicos frequentes</items>
        <items id="description">*</items>
      </items>
      <items code="at0011">
        <items id="text">Requer assistência ociasional, mas é capa de cuidar da maioria de suas necessidades</items>
        <items id="description">*</items>
      </items>
      <items code="at0012">
        <items id="text">uida de si, incapaz para atividades normais ou trabalho ativo</items>
        <items id="description">*</items>
      </items>
      <items code="at0013">
        <items id="text">Atividade normal com esforço, alguns sinais ou sintomas de doença</items>
        <items id="description">*</items>
      </items>
      <items code="at0014">
        <items id="text">Capaz de conduzir atividades normais, sinais ou sintomas menores de doença</items>
        <items id="description">*</items>
      </items>
      <items code="at0015">
        <items id="text">Normal, sem queixas ou evidência de doença</items>
        <items id="description">*</items>
      </items>
      <items code="at0016">
        <items id="text">Item tree</items>
        <items id="description">@ internal @</items>
      </items>
      <items code="at0017">
        <items id="text">Extension</items>
        <items id="description">*Additional information required to extend the model with local content or to align with other reference models or formalisms. (en)</items>
        <items id="comment">*For example: local information requirements; or additional metadata to align with FHIR. (en)</items>
      </items>
    </term_definitions>
    <term_definitions language="nl">
      <items code="at0000">
        <items id="text">Karnofsky Performance Status (KPS) score</items>
        <items id="description">Een meetinstrument gebruikt om functionele mogelijkheden van een individu te kwantificeren.</items>
      </items>
      <items code="at0001">
        <items id="text">History</items>
        <items id="description">@ internal @</items>
      </items>
      <items code="at0002">
        <items id="text">Willekeurig moment in de tijd</items>
        <items id="description">Standaard, ongespecificeerd moment in de tijd dat expliciet gedefinieerd kan worden in een template of tijdens het vastleggen van de data.</items>
      </items>
      <items code="at0003">
        <items id="text">Tree</items>
        <items id="description">@ internal @</items>
      </items>
      <items code="at0004">
        <items id="text">Karnofsky Performance Status</items>
        <items id="description" />
      </items>
      <items code="at0005">
        <items id="text">Overleden</items>
        <items id="description" />
      </items>
      <items code="at0006">
        <items id="text">Moribund</items>
        <items id="description" />
      </items>
      <items code="at0007">
        <items id="text">Ernstig ziek; opname in ziekenhuis is noodzakelijk; actieve ondersteuning vereist</items>
        <items id="description" />
      </items>
      <items code="at0008">
        <items id="text">Geheel bedlegerig; heeft totale verzorging nodig; opname in ziekenhuis geïndiceerd; fatale afloop dreigt nog niet</items>
        <items id="description" />
      </items>
      <items code="at0009">
        <items id="text">Grotendeels bedlegerig; heeft zorg en hulp nodig</items>
        <items id="description" />
      </items>
      <items code="at0010">
        <items id="text">Heeft veel hulp en frequente medische zorg nodig</items>
        <items id="description" />
      </items>
      <items code="at0011">
        <items id="text">Heeft af en toe hulp nodig, maar is in staat grotendeels voor zichzelf te zorgen</items>
        <items id="description" />
      </items>
      <items code="at0012">
        <items id="text">In staat voor zichzelf te zorgen; onmogelijk om normale activiteiten te verrichten of om te werken</items>
        <items id="description" />
      </items>
      <items code="at0013">
        <items id="text">Met inspanning tot normale activiteit in staat</items>
        <items id="description" />
      </items>
      <items code="at0014">
        <items id="text">In staat tot normale activiteit; minimale verschijnselen van de ziekte</items>
        <items id="description" />
      </items>
      <items code="at0015">
        <items id="text">Geen klachten, geen ziekteverschijnselen</items>
        <items id="description" />
      </items>
      <items code="at0016">
        <items id="text">Item tree</items>
        <items id="description">@ internal @</items>
      </items>
      <items code="at0017">
        <items id="text">Uitbreiding</items>
        <items id="description">Extra informatie benodigd voor het uitbreiden van het model met lokale informatie of voor het in lijn brengen met andere referentiemodellen of formalismen.</items>
        <items id="comment">Bijvoorbeeld: lokale informatie eisen of extra metadata om in lijn te brengen met FHIR.</items>
      </items>
    </term_definitions>
    <term_definitions language="nb">
      <items code="at0000">
        <items id="text">Karnofsky Performance Status (KPS) scale</items>
        <items id="description">En vurderingsskala for å beskrive funksjonsnivå/status hos et individ.</items>
      </items>
      <items code="at0001">
        <items id="text">History</items>
        <items id="description">@ internal @</items>
      </items>
      <items code="at0002">
        <items id="text">Uspesifisert tidspunkthendelse</items>
        <items id="description">Standard, uspesifisert tidspunkt som kan defineres mer eksplisitt i et templat eller i en applikasjon.</items>
      </items>
      <items code="at0003">
        <items id="text">Tree</items>
        <items id="description">@ internal @</items>
      </items>
      <items code="at0004">
        <items id="text">Karnofsky performance status</items>
        <items id="description" />
      </items>
      <items code="at0005">
        <items id="text">Død.</items>
        <items id="description" />
      </items>
      <items code="at0006">
        <items id="text">Moribund, dødsprosessen er i sterk frammarsj.</items>
        <items id="description" />
      </items>
      <items code="at0007">
        <items id="text">Svært syk, hospitalisering og understøttende behandling nødvendig.</items>
        <items id="description" />
      </items>
      <items code="at0008">
        <items id="text">Helt ufør, hospitalisering nødvendig, men fare for død er ikke overhengende.</items>
        <items id="description" />
      </items>
      <items code="at0009">
        <items id="text">Ufør, trenger spesiell hjelp og omsorg.</items>
        <items id="description" />
      </items>
      <items code="at0010">
        <items id="text">Trenger betydelig hjelp og stadig medisinsk omsorg.</items>
        <items id="description" />
      </items>
      <items code="at0011">
        <items id="text">Trenger noe hjelp, men klarer stort sett å tilfredsstille egne behov.</items>
        <items id="description" />
      </items>
      <items code="at0012">
        <items id="text">Klarer seg selv, ute av stand til normal aktivitet eller aktivt arbeid.</items>
        <items id="description" />
      </items>
      <items code="at0013">
        <items id="text">Klarer med nød normal aktivitet. Sykdommen gir en del symptomer.</items>
        <items id="description" />
      </items>
      <items code="at0014">
        <items id="text">Klarer normal aktivitet, sykdommen gir lite symptomer.</items>
        <items id="description" />
      </items>
      <items code="at0015">
        <items id="text">Normal, ingen plager eller subjektive tegn på sykdom.</items>
        <items id="description" />
      </items>
      <items code="at0016">
        <items id="text">Item tree</items>
        <items id="description">@ internal @</items>
      </items>
      <items code="at0017">
        <items id="text">Tilleggsinformasjon</items>
        <items id="description">Ytterligere informasjon som trengs for å kunne registrere lokalt definert innhold eller for å tilpasse til andre referansemodeller/formalismer.</items>
        <items id="comment">For eksempel lokale informasjonsbehov eller ytterligere metadata for å kunne tilpasse til tilsvarende konsepter i FHIR.</items>
      </items>
    </term_definitions>
    <term_definitions language="de">
      <items code="at0000">
        <items id="text">Karnofsky-Performance Status (KPS-Skala)</items>
        <items id="description">Eine Bewertungsskala zur Quantifizierung der funktionellen Leistungsfähigkeit einer Person.</items>
      </items>
      <items code="at0001">
        <items id="text">History</items>
        <items id="description">@ internal @</items>
      </items>
      <items code="at0002">
        <items id="text">Beliebiges Ereignis</items>
        <items id="description">Standardwert, ein undefinierter Zeitpunkt, der explizit im Template oder zur Laufzeit der Anwendung definiert werden kann.</items>
      </items>
      <items code="at0003">
        <items id="text">Tree</items>
        <items id="description">@ internal @</items>
      </items>
      <items code="at0004">
        <items id="text">Karnofsky-Performance Status</items>
        <items id="description" />
      </items>
      <items code="at0005">
        <items id="text">Tot</items>
        <items id="description" />
      </items>
      <items code="at0006">
        <items id="text">Sterbend; fatale Prozesse, die schnell voranschreiten</items>
        <items id="description" />
      </items>
      <items code="at0007">
        <items id="text">Schwerkrank; stationäre Aufnahme erforderlich; aktive supportive Behandlung notwendig</items>
        <items id="description" />
      </items>
      <items code="at0008">
        <items id="text">Schwerbehindert; stationäre Aufnahme ist angezeigt, obwohl der Tod nicht unmittelbar bevorsteht</items>
        <items id="description" />
      </items>
      <items code="at0009">
        <items id="text">Behindert; erfordert qualifizierte Pflege und Hilfe</items>
        <items id="description" />
      </items>
      <items code="at0010">
        <items id="text">Benötigt beträchtliche Unterstützung und häufige medizinische Versorgung</items>
        <items id="description" />
      </items>
      <items code="at0011">
        <items id="text">Benötigt gelegentlich fremde Hilfe, ist aber in der Lage, sich um die meisten seiner persönlichen Bedürfnisse zu kümmern</items>
        <items id="description" />
      </items>
      <items code="at0012">
        <items id="text">Selbstversorgend; unfähig, einer normalen Tätigkeit nachzugehen oder aktiv zu arbeiten</items>
        <items id="description" />
      </items>
      <items code="at0013">
        <items id="text">Normale Aktivität mit Anstrengung; einige Anzeichen oder Symptome der Krankheit</items>
        <items id="description" />
      </items>
      <items code="at0014">
        <items id="text">In der Lage, normale Aktivitäten fortzusetzen; geringe Anzeichen oder Symptome einer Krankheit</items>
        <items id="description" />
      </items>
      <items code="at0015">
        <items id="text">Normalzustand; weder Beschwerden noch Symptome sind vorhanden</items>
        <items id="description" />
      </items>
      <items code="at0016">
        <items id="text">Item tree</items>
        <items id="description">@ internal @</items>
      </items>
      <items code="at0017">
        <items id="text">Erweiterung</items>
        <items id="description">Zusätzliche Informationen, die zur Erfassung lokaler Inhalte oder zur Anpassung an andere Referenzmodelle/Formalismen erforderlich sind.</items>
        <items id="comment">Zum Beispiel: Lokale Informationsanforderungen oder zusätzliche Metadaten, um Verknüpfungen mit FHIR herzustellen.</items>
      </items>
    </term_definitions>
    <term_bindings terminology="SNOMED-CT">
      <items code="at0000">
        <value>
          <terminology_id>
            <value>SNOMED-CT</value>
          </terminology_id>
          <code_string>273546003</code_string>
        </value>
      </items>
      <items code="at0004">
        <value>
          <terminology_id>
            <value>SNOMED-CT</value>
          </terminology_id>
          <code_string>761869008</code_string>
        </value>
      </items>
    </term_bindings>
  </ontology>
</archetype>
